Naples-based telehealth · Southwest Florida · Florida · 47 of 50 U.S. states (excluding AK, HI, and AR) · No walk-in address · Call 239-422-6350 · Book Online
Honest Comparison
South Florida Trim Clinic vs Profile by Sanford
One program emphasizes telehealth GLP-1 care; the other has historically centered on coaching and nutrition products. Here is a factual, hedged look at how the two compare so you can make an informed choice.
Based in Naples / Southwest Florida — Telehealth available across Florida and eligible states.
Quick answer
What makes South Florida Trim Clinic different from Profile by Sanford?
South Florida Trim Clinic is a Naples-rooted telehealth practice focused on GLP-1 weight-loss care — semaglutide and tirzepatide when appropriate — with transparent pricing from $149/month and direct phone access at 239-422-6350. Profile by Sanford has historically centered on coaching and meal-replacement products. Offerings can change — verify directly. Results vary and no medication is guaranteed.
Different Models, Different Strengths
Profile by Sanford is a structured weight-management program developed within a large health system. It has traditionally combined personal coaching, nutrition planning, and proprietary meal-replacement products, often delivered through a membership and, in some areas, physical locations. For people who thrive with hands-on coaching and a defined food framework, that structure can be genuinely helpful.
South Florida Trim Clinic is built around a different need. We are a Naples-rooted, 100% telehealth practice centered on medical weight loss in Naples and across Southwest Florida. Rather than selling food products, we focus on medically guided GLP-1 care. After a free consultation and a licensed provider's review of your health history, our providers may discuss semaglutide or tirzepatide when clinically appropriate, with transparent supervision starting at $149/month — see our pricing page for details.
This page is not intended to disparage Profile by Sanford or any company. It is meant to help you compare honestly. If you are new to remote care, read how telehealth weight loss works and our GLP-1 FAQ before deciding what fits your goals.
Compare the Total Monthly Cost of GLP-1 Programs
DON'T JUST COMPARE THE MEDICATION PRICE. COMPARE THE TOTAL COST — AND WHAT YOU GET FOR IT.
Compare medication price, membership or program fees, estimated total monthly cost, prepayment or commitment requirements, patient support and shipping—not just the advertised medication price. Some starting rates require a longer plan or upfront payment; medication, dose and eligibility can also affect the bill.
Pricing checked October 16, 2026
Competitor pricing and program terms can change.
Compare the Total Monthly Cost of GLP-1 Programs
Provider
Starting Medication Price
Membership / Program Fee
Estimated Starting Total / Month
Prepayment / Commitment Required for Price Shown?
Patient Support
Delivery / Shipping
South Florida Trim Clinic
No Membership Fees Ever.
No contract
Free consultation
Medical monitoring
100% telehealth
Available in 47 states (not currently available in Alaska, Hawaii or Arkansas)
$149/month
Medication starts at this price; actual pricing may vary.
$0
No membership fees ever.
$149/month
Estimated starting total.
NO
No required prepayment. No long-term contract.
White-glove patient support
Free consultation and ongoing medical monitoring.
FREE STANDARD SHIPPING
Medication shipped directly to your door. Medication typically ships within 2 business days after the applicable prescription/order is processed.
TrimRx
–GLP-1 + GIP starts at $259/month; the estimated total shown is for the starting GLP-1 option.
$179/month
GLP-1; GLP-1 + GIP from $259/month.
$0
$179/month
For the advertised starting GLP-1 option.
NO
No prepayment for the standard monthly price per published information.
Provider access advertised
Verify the included support services and access with TrimRx.
Free shipping advertised
Tracked shipping is advertised on TrimRx's official site; verify current terms.
Mochi Health
–Longer prepaid membership terms may offer a lower membership rate.
For standard month-to-month. Lower membership may be available with longer prepaid terms.
Patient Support
Care-team access
Membership advertises provider visits and care-team support.
Delivery / Shipping
See provider
–Longer prepaid membership terms may offer a lower membership rate.
Provider: Ro
Estimated Starting Total / Month
About $223–$298/month
Starting Medication Price
From $149/month
Select options.
Membership / Program Fee
About $74–$149/month
About $74/month with qualifying annual prepayment, or about $149/month monthly.
Prepayment / Commitment Required for Price Shown?
YES
Annual prepayment for the $74 membership rate. The monthly plan requires none but costs more.
Patient Support
Provider support
Official plans advertise on-demand provider messaging and ongoing care.
Delivery / Shipping
See provider
–Medication and membership are separate charges. The total range reflects annual-prepaid or monthly membership.
Provider: Hims
Estimated Starting Total / Month
About $298/month
Where $149 medication and $149 membership apply.
Starting Medication Price
From about $149/month
Select options.
Membership / Program Fee
About $149/month
Ongoing membership.
Prepayment / Commitment Required for Price Shown?
PLAN DEPENDENT
Prepayment and commitment depend on the selected plan.
Patient Support
Care-team support
Membership advertises care-team messaging and provider follow-up; response times may vary.
Delivery / Shipping
See provider
–The estimated total applies where both the $149 medication and $149 membership prices apply.
Provider: WeightWatchers Clinic
Estimated Starting Total / Month
About $373–$383/month
Starting Medication Price
From about $299/month
Zepbound.
Membership / Program Fee
About $74–$84/month
About $74/month on qualifying 12-month Med+ or about $84/month on qualifying 6-month plan, after introductory pricing.
Prepayment / Commitment Required for Price Shown?
YES
A qualifying 6- or 12-month Med+ commitment is required for these rates. Some medication offers may involve upfront payment.
Patient Support
See provider
Delivery / Shipping
See provider
–Medication and Med+ membership are separate charges. Ongoing membership rates shown follow introductory pricing and require the specified commitment.
Provider: LifeMD
Estimated Starting Total / Month
$75 program fee + medication cost
Medication cost varies; no combined total is assumed.
Starting Medication Price
VARIES
Membership / Program Fee
From about $75/month
With a qualifying annual plan.
Prepayment / Commitment Required for Price Shown?
YES
The lowest advertised $75/month program rate is tied to a qualifying annual plan. Medication is additional.
Patient Support
See provider
Delivery / Shipping
See provider
–The program fee is not a medication-inclusive total.
* Mochi's advertised starting medication price refers to compounded semaglutide. Compounded drugs are not FDA-approved. The FDA does not review compounded drugs for safety, effectiveness or quality before marketing.
$149
STARTING MEDICATION / MONTH
$0
MEMBERSHIP FEES
$0
REQUIRED PREPAYMENT
No Membership Fees Ever.
MORE THAN A MEDICATION PRICE.
Straightforward pricing backed by personal care from consultation through delivery.
$149 Medication Starting Price
$0 Membership Fees — Ever
$0 Required Prepayment
White-Glove Patient Support
Free Standard Shipping
Direct-To-Your-Door Delivery
Free Consultation
Ongoing Medical Monitoring
No Long-Term Contract
Medication typically ships within 2 business days after the applicable prescription/order is processed. Medication is shipped directly to your door with free standard shipping. Care is 100% telehealth, available in 47 states, excluding Alaska, Hawaii and Arkansas. Eligibility, medication and dosing are determined through medical evaluation; actual pricing may vary.
BEFORE YOU CHOOSE A GLP-1 PROVIDER, ASK THESE QUESTIONS.
1What is the medication price?
2Is there a separate membership fee?
3Is there a medical or program fee?
4Does the advertised price require prepayment?
5Do I have to purchase 6 or 12 months to get that price?
6Does the medication price increase at higher doses?
7Is medical monitoring included?
8Is shipping included?
9How quickly does my medication typically ship?
10Can I speak with someone when I need help?
11Am I locked into a contract?
12What will I ACTUALLY PAY each month?
SEE WHAT YOUR TREATMENT WOULD ACTUALLY COST.
Medication starts at $149 per month with no membership fees ever. No required prepayment. No long-term contract. Free consultation. Free standard shipping. White-glove patient service.
Pricing comparison is based on publicly advertised cash-pay starting prices and program terms reviewed October 16, 2026. Competitor pricing, introductory offers, medications, dosage pricing, membership requirements, shipping terms and program terms may change. Estimated monthly totals are calculated from published starting medication prices plus applicable published ongoing membership or program fees where a reasonable calculation can be made. Estimates are for comparison purposes and do not represent a price quote or guarantee that every patient will pay that amount. Insurance coverage, medication selection, dosage, eligibility, pharmacy fulfillment and other factors may affect actual cost. Verify current pricing and terms directly with each provider. Prescription treatment requires medical evaluation and eligibility.
Compounded drugs are not FDA-approved. The FDA does not review compounded drugs for safety, effectiveness or quality before marketing.
South Florida Trim Clinic connects patients with independent licensed medical providers. Each medical doctor is licensed in the patient's state and makes treatment and prescribing decisions independently, based on professional judgment.
Independent, licensed medical doctors
Medical doctors licensed in your state review your health history, evaluate whether care is appropriate, answer your questions, and make prescribing decisions using their professional judgment.
Eligibility-based treatment
Prescription treatment is only offered when medically appropriate, after you complete an intake and eligibility review.
GLP-1 options when appropriate
Treatment plans may include GLP-1 options such as semaglutide or tirzepatide when clinically appropriate for you.
Secure messages & regular check-ins
Patients can use secure messaging to ask questions and receive regular check-ins to review progress and discuss concerns.
Results vary and no medication is guaranteed. Telehealth weight-loss care is not a replacement for emergency care — emergency care is not provided through this website. If you are experiencing a medical emergency, call 911.
Frequently Asked Questions
How is South Florida Trim Clinic different from Profile by Sanford?+
The two programs emphasize different things. South Florida Trim Clinic is a Naples-rooted telehealth practice focused on GLP-1 medical weight loss — such as semaglutide and tirzepatide when appropriate — with transparent supervision from $149/month and phone access at 239-422-6350. Profile by Sanford is a membership weight-management program that typically centers on coaching, nutrition planning, and meal-replacement products, with some locations. Offerings can change over time, so verify current details directly with each provider. Results vary and no medication is guaranteed.
Does South Florida Trim Clinic use meal-replacement products like Profile by Sanford?+
No. South Florida Trim Clinic does not sell branded meal-replacement products or food packages. Our focus is medically guided GLP-1 care reviewed by licensed providers, paired with patient education about appetite and food noise. Profile by Sanford has historically built its program around coaching and proprietary nutrition products. Both can be reasonable approaches depending on your goals; we encourage you to compare what each includes directly with the provider before choosing. Not everyone qualifies and results vary.
Can I get care from home with South Florida Trim Clinic?+
Yes. South Florida Trim Clinic is a 100% telehealth practice, so your free consultation, eligibility review, and follow-ups happen by phone or video from home anywhere in Collier County or Southwest Florida. Coaching-and-product programs like Profile by Sanford may involve in-person coaching or location visits; formats can change, so confirm current options directly. Telehealth availability may vary by state, and telehealth weight-loss care is not a replacement for emergency care.
What does South Florida Trim Clinic cost compared with a coaching membership?+
South Florida Trim Clinic's GLP-1 medication starts at $149/month — that is the starting price, which may vary by medication type and potency; you can see the breakdown on our pricing page. Coaching-and-product memberships such as Profile by Sanford may bundle food products, coaching, and fees, so total cost can vary widely. Because pricing changes over time, compare costs directly with each provider before deciding. Eligibility is determined by a licensed provider and results vary.
Compare for Yourself — Start With a Free Consultation
A licensed provider will review your health history and give you honest guidance about whether GLP-1 telehealth care may be right for you — no pressure and no judgment. Serving Naples, Collier County, and all of Southwest Florida.
Naples, FL — Telehealth across Florida and eligible states
Results vary and no medication is guaranteed. Eligibility is determined by a licensed provider, and not everyone qualifies. Telehealth weight-loss care is not a replacement for emergency care. This page is for informational purposes only and is not intended to disparage any competitor.
